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Granuliberin R
CAS No. 64704-41-2
Granuliberin R( ——— )
Catalog No. M41894 CAS No. 64704-41-2
Granuliberin R is a new mast cell degranulating peptide comes from amphibian, can be isolated from the skin of frog Rana rugosa. Granuliberin R is a dodecapeptide, can act on rat peritoneal mast cell to liberate granules and release histamine.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameGranuliberin R
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NoteResearch use only, not for human use.
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Brief DescriptionGranuliberin R is a new mast cell degranulating peptide comes from amphibian, can be isolated from the skin of frog Rana rugosa. Granuliberin R is a dodecapeptide, can act on rat peritoneal mast cell to liberate granules and release histamine.
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DescriptionGranuliberin R is a new mast cell degranulating peptide comes from amphibian, can be isolated from the skin of frog Rana rugosa.
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In VitroGranuliberin R (10 μg/mL) does not alter the release of catecholamines and adenine nucleotides from cultured adrenal chromaffin cells, while the Mastoparan (10 μg/mL) increases both of them.
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In VivoGranuliberin R (0.1 mg/mL, 1 μg/mL, and 10 ng/mL; injection; single dose for 60 s) interfere in the proliferation of oral keratinocytes and the activity of connective tissue cells when treatment is conducted into rats mandibular gingiva in the vicinity of the right mental foramen.
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Synonyms———
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PathwayOthers
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TargetOther Targets
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Recptor———
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Research Area———
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Indication———
Chemical Information
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CAS Number64704-41-2
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Formula Weight1422.71
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Molecular FormulaC69H103N19O14
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Purity>98% (HPLC)
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Solubility———
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Nakajima T, et al. A new mast cell degranulating peptide, granuliberin-R, in the frog (Rana rugosa) skin. Chem Pharm Bull (Tokyo). 1977 Sep;25(9):2464-5.?
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